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Peer-reviewed veterinary case report

Eye infections and ulcers caused by canine herpesvirus in adult dogs

By Ledbetter, E C·Published in New Zealand veterinary journal·2013·Department of Clinical Services, United States·View original on PubMed

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Original publication title: Canine herpesvirus-1 ocular diseases of mature dogs.

Species:
dog

Plain-English summary

A mature dog with eye problems may be suffering from an infection caused by canine herpesvirus-1 (CHV-1). This virus can lead to various eye issues, such as inflammation of the eyelids (blepharitis), redness and swelling of the eye (conjunctivitis), and corneal ulcers. These conditions can occur when the virus reactivates, especially in dogs that are on immunosuppressive medications. As more dogs are treated for chronic health issues, the risk of CHV-1 eye infections could become more common. It's important to consult your veterinarian if your dog shows any signs of eye discomfort or unusual symptoms.

People also search for: dog eye problems · canine herpesvirus symptoms · dog conjunctivitis treatment · what causes dog blepharitis · dog corneal ulcer treatment

Abstract

Canine herpesvirus-1 (CHV-1) is an alphaherpesvirus with a host range restricted to canids. Latent CHV-1 infection is endemic in domestic dog populations worldwide. The role of CHV-1 in severe systemic neonatal infections and as an aetiology of infectious infertility and abortion has been appreciated for decades; however, ocular diseases of mature dogs conclusively associated with CHV-1 infection were only recently described. Clinically, CHV-1 infection may produce a diverse range of adnexal and ocular surface lesions in mature dogs, including blepharitis, conjunctivitis, ulcerative keratitis, and nonulcerative keratitis. These conditions can develop during primary or recurrent ocular CHV-1 infection. Recurrent CHV-1 infections associated with reactivation of latent virus may be observed during a variety of situations and in association with numerous different viral reactivation stimuli, including the administration of immunosuppressive pharmaceuticals. The understanding of CHV-1 pathophysiology and ocular infections in mature dogs has expanded rapidly during the past few years, but much remains to be elucidated. As the number of dogs living with chronic immunomodulatory systemic diseases and receiving immunosuppressive therapeutics continues to grow, the clinical importance of CHV-1 ocular infections is also likely to increase.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23438442/