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Peer-reviewed veterinary case report

Canine herpesvirus effects during pregnancy and luteal phase in dogs

By Ström Holst, B et al.·Published in Reproduction in domestic animals = Zuchthygiene·2012·Department of Clinical Sciences·View original on PubMed

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Original publication title: Canine herpesvirus during pregnancy and non-pregnant luteal phase.

Species:
dog

Plain-English summary

A group of pregnant dogs was studied to see how canine herpesvirus (CHV) might affect their pregnancies. The researchers found that while all the dogs had antibodies to CHV, two of the unvaccinated pregnant dogs showed an increase in virus levels, but this did not harm their pregnancies or the size of their litters. Vaccination during pregnancy did not seem to change the outcomes either. Overall, the study showed that CHV did not appear to cause problems during pregnancy in the dogs observed.

People also search for: dog pregnancy herpesvirus · canine herpesvirus effects on puppies · vaccinated pregnant dog health risks

Abstract

Canine herpesvirus (CHV) is a widespread infection among dogs that typically get latently infected after exposure and can reactivate the infection after stress. The aim of the present study was to study the effects of latent CHV infection during pregnancy on pregnancy outcome, and to study if there are signs of genital viral reactivation during pregnancy or during non-pregnant luteal phase. Twelve mated bitches and eight control bitches were followed and sampled regularly during pregnancy or non-pregnant luteal phase. Blood samples were taken for antibody analysis and vaginal swabs for real-time PCR analysis. Three of the pregnant bitches were vaccinated against CHV during pregnancy. All bitches had antibodies to CHV. Two pregnant bitches that were not vaccinated had a twofold or larger increase in CHV titre, with no negative effects detected on pregnancy. Higher titres were not associated with smaller litters or with vaccination. There was no consistent variation in antibody titres due to pregnancy or non-pregnant luteal phase. Vaginal excretion of CHV was not detected from any of the bitches.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23279539/