Peer-reviewed veterinary case report
Canine Idiopathic Chronic Hepatitis.
- Journal:
- The Veterinary clinics of North America. Small animal practice
- Year:
- 2017
- Authors:
- Bexfield, Nick
- Affiliation:
- School of Veterinary Medicine and Science · United Kingdom
- Species:
- dog
Plain-English summary
This article discusses a condition called chronic hepatitis in dogs, which is when the liver becomes inflamed and damaged over time. The condition can look different depending on the dog's breed, and one common cause is the buildup of copper in the liver. However, if copper isn't the cause, the condition is labeled as idiopathic chronic hepatitis, meaning the exact reason is unknown. The article also covers how this condition is diagnosed and managed, offering insights into its symptoms and treatment options. Overall, it aims to help veterinarians better understand and treat this liver issue in dogs.
Abstract
The World Small Animal Veterinary Association's Liver Standardization Group produced standardized criteria for the histologic diagnosis of canine chronic hepatitis (CH). They define CH by the presence of hepatocellular apoptosis or necrosis, a variable mononuclear or mixed inflammatory cell infiltrate, regeneration, and fibrosis. There are variations in histologic appearance between breeds. Hepatic copper accumulation is an important cause of canine CH. However, where copper accumulation has been ruled out, dogs are said to have idiopathic CH. This article reviews theories regarding the etiopathogenesis of canine CH other than copper accumulation, and its clinical features, diagnostic findings, and management.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/28063746/