Peer-reviewed veterinary case report
Puppy with rare heart muscle disease and valve problems
By Vilcu, Maria et al.·Published in BMC veterinary research·2020·University of Agricultural Science and Veterinary Medicine·View original on PubMed →
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Original publication title: Canine infantile left ventricular noncompaction.
- Species:
- dog
Plain-English summary
A 7-week-old German Shorthaired Pointer mix was brought to the vet because he was in poor condition, had trouble exercising, and was having difficulty breathing. The vet found a heart murmur and diagnosed him with several serious heart issues, including a rare condition called left ventricular noncompaction, which affects the heart's structure. Unfortunately, this condition was confirmed after the puppy passed away, highlighting the need for awareness of this heart disease in young dogs.
People also search for: puppy breathing problems · German Shorthaired Pointer heart disease · dog heart murmur symptoms
Abstract
BACKGROUND: Left ventricular noncompaction (LVNC) is a rare form of cardiomyopathy currently described in humans and cats. It consists of a spongy myocardium characterized by prominent trabeculation and deep recesses involving more than 50% of the ventricular thickness. We describe the clinical and pathological features of LVNC combined with tricuspid valve dysplasia, double-orifice tricuspid valve and severe pulmonary stenosis in a puppy. In addition, we briefly review the LVNC causes, pathogenesis, forms and current diagnostic criteria. CASE PRESENTATION: A seven-week-old intact German Shorthaired Pointer-cross male was presented with a poor body condition, exercise intolerance and dyspnea. Clinical exam identified a bilateral systolic murmur (grade IV/VI over the right heart base and grade III/VI over the left heart base). Echocardiography identified tricuspid valve dysplasia, mild mitral regurgitation, and severe pulmonic stenosis with a trans-valvar systolic pressure gradient of 106 mmHg. Left ventricular noncompaction was diagnosed by necropsy and further confirmed histopathologically by the presence of two distinct myocardial layers: an inner noncompacted zone covering more than 50% of ventricular thickness containing prominent trabeculation and deep recesses, and an outer zone of compact myocardium. CONCLUSIONS: This is the first case describing LVNC in a canine patient, supporting the introduction of this form of heart disease as a differential diagnosis for cardiomyopathies in juvenile and adult dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32703195/