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Peer-reviewed veterinary case report

Dog with low aldosterone causing collapse and thirst

By Raj, Jennifer et al.·Published in Veterinary Record Case Reports·2021·Small Animal Internal Medicine Dick White Referrals Ltd Six Mile Bottom Cambridgeshire UK, United Kingdom·View original on Crossref

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Original publication title: Canine isolated hypoaldosteronism

Species:
dog

Plain-English summary

A 2-year-old female neutered English bull terrier was brought to the vet because she was acting depressed, seemed lethargic, was drinking and urinating more than usual, and had collapsed twice. After some tests, the vet found that her aldosterone levels were very low, which is important for regulating salt and potassium in the body. The dog was treated with a mineralocorticoid supplement, which quickly improved her symptoms and balanced her electrolytes. She has been doing well on this treatment for five years now.

People also search for: dog depression and lethargy · English bull terrier collapse · hypoaldosteronism treatment in dogs

Abstract

Abstract A 2‐year‐old female neutered English bull terrier presented with a history of behavioural change (depression, lethargy, avoidance of light), a mild increase in thirst and urination and two episodes of collapse. General physical and neurological examinations were unremarkable. Initial investigations documented hyponatremia and hyperkalaemia. An adrenocorticotropic hormone (ACTH) stimulation test excluded hypocortisolism. Aldosterone concentrations obtained pre‐ and post‐ACTH stimulation were both undetectably low. Paired renin and aldosterone assays confirmed hyperreninemic hypoaldosteronism. The patient was treated with oral mineralocorticoid supplementation which resulted in a rapid improvement in both clinical signs and electrolyte concentrations; she remained well on treatment during a 5‐year follow‐up period. Isolated hypoaldosteronism is infrequently reported in the dog but should be considered in cases where hypoadrenocorticism is suspected based on electrolyte abnormalities, but hypocortisolism has been excluded.

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Original publication on Crossref: https://doi.org/10.1002/vrc2.29