Peer-reviewed veterinary case report
Dog with painless skin nodules caused by rare mycobacteria in Brazil
By Biezus, Giovana et al.·Published in Topics in companion animal medicine·2022·Department of Veterinary Medicine, Brazil·View original on PubMed →
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Original publication title: Canine Leproid Granuloma (CLG) Caused by Mycobacterial Species Closely Related to Members of Mycobacterium Simiae Complex in a Dog in Brazil.
- Species:
- dog
Plain-English summary
A 12-year-old male Labrador Retriever was brought in with painless skin lesions that had been getting worse over the past two weeks. The dog had ulcerated nodules with crusts on its ears and feet. After various tests, including blood work and skin biopsies, the vet diagnosed the dog with canine leproid granuloma (CLG), a skin condition caused by a type of mycobacteria. Although the bacterial culture didn’t show any growth, DNA testing confirmed the presence of the mycobacterial species. The dog’s treatment plan would typically include medications to manage the condition, but specific outcomes were not detailed in the report.
People also search for: dog skin lesions treatment · Labrador Retriever skin problems · canine leproid granuloma symptoms
Abstract
This report describes the clinical features and molecular diagnosis of a case of canine leproid granuloma (CLG) caused by mycobacterial strains of the Mycobacterium simiae complex in Brazil. A 12-year-old non-neutered male Labrador Retriever dog was presented with a 2-week history of progressive painless cutaneous lesions. Ulcerated nodules with hematic crusts were observed on the dorsal surface of the right and left pinna and on the metacarpal, metatarsal, and digits. Complete blood count, serum biochemistry, aspiration cytology of cutaneous lesions, biopsy for histopathological evaluation, culture for aerobic and anaerobic bacteria, polymerase chain reaction and DNA sequencing to identify mycobacterial species were performed. According to the clinical and histopathological findings, a diagnosis of CLG was established. Despite the negative result of the bacterial culture, mycobacterial identification was made by sequencing the hsp65 gene. Our findings highlight that mycobacterial species closely related to members of the M simiae clade can be causative agents of CLG.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35644473/