Peer-reviewed veterinary case report
Eye tumors in dogs after ciliary body ablation with gentamicin
By Duke, Felicia D et al.·Published in Veterinary ophthalmology·2013·Department of Pathobiological Sciences, United States·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Canine ocular tumors following ciliary body ablation with intravitreal gentamicin.
- Species:
- dog
Plain-English summary
A review of eye tumors in dogs found that nearly 40% of dogs who had a procedure called ciliary body ablation (using gentamicin to treat glaucoma) later developed eye tumors, particularly iridociliary tumors. These tumors are often benign, but in this case, many were found to be malignant. The findings suggest that some tumors may have been present but not detected during the initial treatment. This highlights the need for careful consideration before using this treatment on dogs that do not have any visible eye disease.
People also search for: dog eye tumors after glaucoma treatment · ciliary body ablation side effects · iridociliary tumors in dogs
Abstract
Iridociliary tumors are the second most common primary ocular tumor in dogs and are usually benign. A review of the Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW) database in 2009 suggested a potential correlation between malignant iridociliary epithelial tumors and ciliary body ablation by intravitreal gentamicin injection for the treatment of glaucoma. The purpose of this case series was to determine whether there is evidence of such a correlation in the COPLOW collection. Mining of the COPLOW database revealed that a significant number (39.5%) of canine globes with a history of ciliary body ablation were subsequently diagnosed with primary ocular tumors at enucleation, most commonly iridociliary epithelial tumors and melanocytic tumors. It is possible that neoplasia was present but unrecognized at the time of ciliary body ablation. These tumors had a higher than expected incidence of malignancy. These cases underscore the importance of reserving ciliary body ablation with gentamicin for disease-free eyes.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22812389/