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Peer-reviewed veterinary case report

Canine ovarian serous papillary adenocarcinoma with neoplastic hypercalcemia.

Journal:
The Journal of veterinary medical science
Year:
2006
Authors:
Hori, Yasutomo et al.
Affiliation:
Veterinary Teaching Hospital · Japan
Species:
dog

Abstract

A female golden retriever was referred to assess a history of a palpable abdominal mass. A serum chemistry analysis revealed elevated concentrations of blood urea nitrogen, creatinine, calcium, and parathyroid hormone-related protein (PTH-rP). Exploratory laparotomy revealed an ovoid mass within the right ovary. This mass was removed surgically by performing an ovariohysterectomy. The right ovarian mass was diagnosed as a serous papillary adenocarcinoma. Following surgery, the dog recovered, and the serum calcium and PTH-rP concentrations decreased. Therefore, concentrations of PTH-rP and calcium might be associated with serous papillary adenocarcinomas. Serial evaluation of the serum PTH-rP and calcium was useful for evaluating the prognosis.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17019069/