Canine parvovirus: Environmental effects on infectivity

Abstract

SUMMARY Effects of various environments on the infectivity of canine parvovirus-2 (cpv-2) were studied. When cpv-2 was subjected to several controlled indoor environments, the virus remained infective at approximate initial inoculation amount (median tissue culture infective dose [tcid50] = 105.5/ml) for 12 months at temperatures < −20 C, decreased to tcid50 of 102.3/ml by 12 months at 4 C, and had a tcid50 of < 101ml at room temperature (20 C) or higher in < 2 months. The cpv-2 subjected to outdoor environments was not infective beyond 5 months, except that kept in areas protected from sunlight and drying conditions. The virus surviving in the outdoor environments was not infective for study dogs, whereas the virus maintained at < 20 C was.