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Peer-reviewed veterinary case report

Canine parvovirus infection patterns in dogs with gastroenteritis

By Truyen, Lotta Henni et al.·Published in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]·2024·University of Veterinary Medicine Hannover, Germany·View original on PubMed

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Original publication title: Canine parvovirus type 2 (CPV-2) serological and molecular patterns in dogs with viral gastroenteritis from southern Brazil.

Species:
dog

Plain-English summary

A group of dogs in southern Brazil with symptoms of vomiting and diarrhea were tested for canine parvovirus type 2 (CPV-2), a highly contagious virus that can cause severe illness, especially in puppies. The study found that 40% of the dogs were infected with CPV-2, and those who were unvaccinated had a much higher risk of infection compared to fully vaccinated dogs. Vaccination significantly reduced the chances of getting the virus, showing that it is crucial for protecting pets. The findings highlight the importance of keeping dogs up to date on their vaccinations to prevent serious health issues.

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Abstract

Canine Parvovirus type 2 (CPV-2) is a highly contagious virus that can cause severe systemic disease with gastroenteric symptoms in dogs, particularly in young puppies. Originating from the feline parvovirus in the late 1970s, it swiftly propagated globally, instigating a pandemic in dogs. Despite vaccination advancements, CPV-2 remains a substantial challenge for veterinary professionals and pet owners. This study aimed to contribute knowledge about the current situation of CPV-2 among dogs in southern Brazil. In this study, the sera of 125 dogs (mostly with gastroenteritis symptoms) were screened for antibodies against CPV-2 and their faeces for the virus itself. The results showed that 40% (50/125) of dogs were infected with CPV-2. Most animals (65.5%) had previously been exposed to CPV-2 (with serotitres equal or above 1:40), and only 37.6% had protective antibody titres equal or above 1:80. The findings have also demonstrated that vaccination against CPV-2 significantly reduced the risk of infection, with positive cases decreasing from 56.9% (unvaccinated) to 2.0% (fully vaccinated). Furthermore, the prevalence of CPV-2 decreased as dogs aged, with younger dogs and those with an incomplete or non-existent vaccination history at the highest risk of infection. In conclusion, this study provides valuable insight into the prevalence and risk factors associated with CPV-2 infection in dogs in southern Brazil, thereby providing valuable knowledge for the improvement of veterinary care and pet health.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38407780/