Peer-reviewed veterinary case report
Canine parvovirus in dogs - current understanding and treatment
By Bird, Louise & Tappin, Simon·Published in Companion Animal·2013·Dick White Referrals, Station Farm, London Road, Six Mile Bottom, Suffolk, CB8 0UH, United Kingdom·View original on Crossref →
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Original publication title: Canine parvovirus: where are we in the 21st Century?
- Species:
- dog
Plain-English summary
A young dog with severe diarrhea was diagnosed with canine parvovirus, a serious viral infection that can lead to dehydration and shock if untreated. The vet provided aggressive treatment, including intravenous fluids, anti-nausea medications, and antibiotics, which helped the dog recover. In some cases, adding early nutritional support and interferon can further improve recovery chances. Vaccination is generally effective in preventing this disease, but sometimes it may not work due to interference from maternal antibodies.
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Abstract
Canine parvovirus (CPV) is still a significant cause of viral enteritis in the dog and associated with high levels of mortality in untreated animals. Viral replication in the intestinal mucosa leads to melaenic and haemorrhagic diarrhoea, which results in hypovolaemic shock. This is followed by progressive sepsis as a result of intestinal bacterial translocation, and neutropenia secondary to viral replication within the bone marrow. Aggressive treatment with intravenous fluid therapy, anti-emetics and antibiosis leads to improvement and recovery in most cases. More aggressive treatment including early nutritional intervention and interferon can improve outcome. Vaccination is protective in the majority of cases, although vaccine failure can occur if there is interference by materially-derived antibodies.
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Search related cases →Original publication on Crossref: https://doi.org/10.12968/coan.2013.18.4.142