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Peer-reviewed veterinary case report

Survival and recovery after spinal tumor treatment in 34 dogs

By Lacassagne, K et al.·Published in Veterinary and comparative oncology·2018·Department of Surgery, United States·View original on PubMed

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Original publication title: Canine spinal meningiomas and nerve sheath tumours in 34 dogs (2008-2016): Distribution and long-term outcome based upon histopathology and treatment modality.

Species:
dog

Plain-English summary

A group of 34 dogs with spinal tumors, specifically meningiomas or nerve sheath tumors, were treated with surgery and/or radiation therapy. Dogs with meningiomas lived significantly longer, with an average survival of about 508 days, compared to 187 days for those with nerve sheath tumors. For dogs that had surgery and then received radiation therapy, they gained an extra 125 to 346 days of life. Overall, the study found that adding radiation therapy can help extend survival time for dogs with these types of tumors.

People also search for: dog spinal tumor treatment · meningioma in dogs prognosis · nerve sheath tumor survival time

Abstract

The purpose of this retrospective, multicentre case series was to describe the outcome following surgery and/or radiation of spinal meningiomas and nerve sheath tumours (NSTs) based upon treatment modality, with a specific aim to evaluate the survival times and time to recurrence following treatment for each histopathological diagnosis. Our hypothesis was that the addition of radiation therapy modalities to treatment will yield longer time to recurrence of clinical signs and survival time. Thirty-four dogs met the inclusion criteria of histopathologically diagnosed extramedullary spinal meningioma or NST. Sixteen extramedullary spinal meningiomas and 18 NSTs were diagnosed. A diagnosis of meningioma was associated with a significantly longer survival time compared with NSTs, with median survival times (MST) of 508 days (95% confidence interval [CI]: 66-881) vs 187 days (95% CI: 76-433; P = .02). Dogs (seven) treated with stereotactic radiation therapy (SRT) for recurrence after surgery alone or SRT alone as their initial treatment gained an additional 125 to 346 days survival time.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/29363264/