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Peer-reviewed veterinary case report

Canine transmissible venereal tumor in 64 dogs in Morocco 2020-2023

By Nadia Laissaoui et al.·Published in Open Veterinary Journal·2024·Agronomy and Veterinary Institute Hassan II, Madinat Al Irfane, PO Box 6202 Rabat, Morocco., LY·View original on DOAJ

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Original publication title: Canine transmissible venereal tumour in Morocco: Clinical and pathological findings in 64 dogs – Insights from a descriptive epidemiological study (2020-2023)

Species:
dog

Plain-English summary

A 3-year-old male cross-breed dog in Morocco was diagnosed with a contagious tumor called canine transmissible venereal tumor (CTVT), which typically appears on the genital area. In a study of 64 dogs with this condition, most were young and cross-breeds, with some cases showing the tumor in unusual locations like the skin and nasal cavity. Early diagnosis was possible through cytology in a couple of instances, and histology tests helped confirm the diagnosis. Understanding this tumor's characteristics is important for managing and preventing its spread among dogs.

People also search for: dog genital tumor symptoms · CTVT treatment for dogs · contagious tumors in dogs

Abstract

Background: Canine transmissible venereal tumour (CTVT) is a widely spread, contagious neoplasm commonly found in dogs. Mostly affects the external genitalia, however, it may also exhibit unusual clinical presentations. Aim: To describe the epidemiology, clinical appearance, cytologic and histopathologic features of dogs with TVT in Morocco. Methods: Within the realm of a nation-wide study on canine and feline tumours in Morocco between September 2020 and March 2023, dogs with histologically diagnosed TVT were identified and data on epidemiologic, clinical as well as cytologic and histologic features compiled and analyzed. Results: A total of 64 cases of canine TVT were diagnosed. 52 dogs were cross-breed (81.2%) while 4 Siberian Huskies (6.2%) and 3 German shepherds (4.7%) were the most affected pure-breed dogs. Median age of dogs at diagnosis was 3 years (range, 1-10years) and male gender was more common (male:female ratio; 1.3:1). Tumour was located exclusively in the genital area in 58 cases (90.6%), whereas 6 dogs (9.4%) had an atypical occurrence of TVT with locations including skin and nasal cavity. Cytology allowed for an early diagnosis in 2 cases. Histology revealed no differences between the genital and extragenital forms. Immunohistochemistry was necessary in 4 cases and revealed positive staining for vimentin and Alpha-1-antitrypsin, negative marking for CD3, CD20 and AE1/AE3, and low cytoplasmic labeling for lysozyme. Conclusion: CTVT is a widely distributed neoplasm in Morocco, mostly showing presence in young, cross-breed, and oftentimes stray dogs. Adequate understanding of this tumour's epidemiological features is necessary for its management and eradication. [Open Vet J 2024; 14(5.000): 1206-1215]

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Original publication on DOAJ: https://doi.org/10.5455/OVJ.2024.v14.i5.16