Peer-reviewed veterinary case report
Cat developed tail and toe tissue death from carbimazole side effect
By Bowlt, K et al.·Published in The Journal of small animal practice·2014·Animal Health Trust·View original on PubMed →
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Original publication title: Carbimazole-associated hypersensitivity vasculitis in a cat.
- Species:
- cat
Plain-English summary
A 12-year-old cat with hyperthyroidism developed severe skin problems, including necrosis (tissue death) on its tail and toes, after starting treatment with carbimazole, a medication used to manage the condition. The cat also had kidney issues due to reduced blood flow to the kidneys. After the vet stopped the carbimazole, the cat's condition stabilized, and the symptoms improved. This case highlights the importance of monitoring for side effects when using this medication.
People also search for: cat hyperthyroidism treatment · carbimazole side effects in cats · cat skin problems after medication
Abstract
Feline hyperthyroidism can be treated medically, surgically or with radioactive iodine. Carbimazole inhibits both triiodothyronine and thyroxine synthesis in the thyroid gland and reported side effects include mild eosinophilia, leucopenia and lymphocytosis, thrombocytopenia, elevated liver enzyme activities, gastrointestinal signs and skin abnormalities. This case report describes a cat with carbimazole-associated apparent hypersensitivity vasculitis causing digital and tail necrosis, with multiple renal infarcts. Withdrawal of carbimazole resulted in stable disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24255992/