Peer-reviewed veterinary case report
Cardiac Antigen Implicated in ICI-Linked Myocarditis.
- Journal:
- Cancer discovery
- Year:
- 2023
Abstract
Autoreactive T cells directed against the cardiac muscle-specific antigen α-myosin underlie the heart inflammation experienced by some recipients of immune checkpoint inhibitors. The findings, from mouse models and a handful of patients, could help researchers develop strategies to prevent or treat the drug-related toxicity.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/36583609/