Peer-reviewed veterinary case report
Heart biomarker levels in cats with high pancreatic lipase
By Cridge, Harry et al.·Published in The Veterinary record·2025·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: Cardiac biomarker concentrations in cats with elevated pancreatic lipase concentrations.
- Species:
- cat
Plain-English summary
A group of cats with high levels of pancreatic lipase (a sign of pancreatitis) had their heart health checked by measuring specific cardiac markers. Out of 20 cats with elevated pancreatic lipase, 5 showed higher than normal levels of a heart marker called NT-proBNP, indicating potential heart stress. However, the overall relationship between pancreatic lipase levels and heart markers wasn't strong. This suggests that while some cats with pancreatitis may also have heart issues, the connection isn't clear-cut. If your cat has pancreatitis, it might be worth discussing heart health with your vet.
People also search for: cat pancreatitis symptoms · elevated cardiac markers in cats · cat heart problems treatment
Abstract
BACKGROUND: Cardiac biomarker concentrations are elevated in dogs with pancreatitis, but it is unknown if this is also the case for cats. METHODS: The serum feline pancreatic lipase immunoreactivity (fPLI) of serum samples from 60 cats was quantified using the Spec fPL assay. Serum N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high-sensitivity cardiac troponin I (HST) concentrations were also measured using commercial assays. RESULTS: Five of 20 cats with fPLI concentrations of 8.8 mg/L or more had above reference interval NT-proBNP concentrations. Serum NT-proBNP concentrations were not correlated with fPLI concentrations (p = 0.31) and were not different in each diagnostic category for fPLI results (p = 0.24). Serum HST concentrations were positively correlated with fPLI concentrations (r = 0.278, 95% confidence interval: 0.02‒0.50, p = 0.03). However, they were not significantly different in each diagnostic category for fPLI results (p = 0.16). LIMITATIONS: Unidentified co-variates could contribute to the association between fPLI and cardiac biomarker concentrations. CONCLUSIONS: Cats with elevated fPLI concentrations may have elevated cardiac biomarker concentrations.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39285679/