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Peer-reviewed veterinary case report

Cat with heart lymphoma causing severe lung artery narrowing

By Stout, A et al.·Published in Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology·2025·Department of Veterinary Medicine, United Kingdom·View original on PubMed

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Original publication title: Cardiac lymphoma causing severe pulmonary stenosis in a cat.

Species:
cat

Plain-English summary

A 9-year-old domestic shorthair cat was brought to the vet because it was drinking and urinating more than usual, eating less, and losing weight over the past month. When examined, the cat was having trouble breathing, and tests showed a large mass in the heart affecting the pulmonary valve, which was causing severe heart problems. Unfortunately, the mass was identified as lymphoma, a type of cancer, and it had spread to several organs. The cat's condition was severe, and it did not survive.

People also search for: cat breathing problems · lymphoma in cats · cat weight loss and increased thirst · pulmonary stenosis in cats

Abstract

A nine-year-old, domestic shorthair cat was referred for investigation of a suspected renal mass, polyuria, polydipsia, hyporexia and weight loss of one month's duration; no respiratory signs were reported. On presentation, the cat had marked respiratory effort. Thoracic auscultation revealed reduced heart and lung sounds bilaterally. Transthoracic echocardiography revealed a large pleural effusion and an extensive, homogenous mass within the right ventricular outflow tract, invading the pulmonary valve and causing severe infundibular and valvular pulmonary stenosis and right atrial and ventricular dilatation. The mass extended to, and infiltrated, the right ventricular free wall. Postmortem examination confirmed the presence of a mass associated with the pulmonary valve extending into the right ventricle and infiltrating the right ventricular and right atrial myocardium, resulting in severe infundibular and valvular pulmonary stenosis. Histopathology showed disseminated intermediate to large cell lymphoma affecting the kidney, myocardium, pulmonary valve, pancreas, diaphragm and adrenal glands.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40795482/