Peer-reviewed veterinary case report
Heart and breathing effects of desflurane and sevoflurane anesthesia
By Souza, Almir Pereira et al.·Published in Journal of feline medicine and surgery·2005·Department of Veterinary Clinics and Surgery, Brazil·View original on PubMed →
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Original publication title: Cardiopulmonary and acid-base effects of desflurane and sevoflurane in spontaneously breathing cats.
- Species:
- cat
Plain-English summary
A study looked at how two types of anesthesia, desflurane and sevoflurane, affected cats while they were breathing on their own. The researchers measured various health indicators, including heart rate and blood pressure, during the anesthesia. They found that both anesthetics lowered heart and respiratory rates but kept them stable during the procedure. While both caused some temporary breathing issues, they were still considered safe for short-term use in cats.
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Abstract
The cardiopulmonary effects of desflurane and sevoflurane anesthesia were compared in cats breathing spontaneously. Heart (HR) and respiratory (RR) rates; systolic (SAP), diastolic (DAP) and mean arterial (MAP) pressures; partial pressure of end tidal carbon dioxide (PETCO2), arterial blood pH (pH), arterial partial pressure of oxygen (PaO2) and carbon dioxide (PaCO2); base deficit (BD), arterial oxygen saturation (SaO2) and bicarbonate ion concentration (HCO3) were measured. Anesthesia was induced with propofol (8+/-2.3mg/kg IV) and maintained with desflurane (GD) or sevoflurane (GS), both at 1.3 MAC. Data were analyzed by analysis of variance (ANOVA), followed by the Tukey test (P<0.05). Both anesthetics showed similar effects. HR and RR decreased when compared to the basal values, but remained constant during inhalant anesthesia and PETCO2 increased with time. Both anesthetics caused acidemia and hypercapnia, but BD stayed within normal limits. Therefore, despite reducing HR and SAP (GD) when compared to the basal values, desflurane and sevoflurane provide good stability of the cardiovascular parameters during a short period of inhalant anesthesia (T20-T60). However, both volatile anesthetics cause acute respiratory acidosis in cats breathing spontaneously.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15771945/