Peer-reviewed veterinary case report
Miniature dachshund with forebrain tumor treated by surgery and chemo
By Nakamoto, Yuya et al.·Published in The Journal of veterinary medical science·2016·Kyoto Animal Referral Medical Center, Japan·View original on PubMed →
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Original publication title: Case of a miniature dachshund with a primitive neuroectodermal tumor confined to the forebrain region treated with a combination of surgery and chemotherapy.
- Species:
- dog
Plain-English summary
A 9-year-old miniature dachshund was brought to the vet because it was drinking and urinating more than usual and seemed depressed. An MRI showed a large tumor in the dog's brain, which was surgically removed and identified as a primitive neuroectodermal tumor (PNET). Although the dog initially improved, the tumor came back, and the dog started having cluster seizures a year later, ultimately leading to its death. This case highlights the challenges of treating brain tumors in dogs, even with surgery and chemotherapy.
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Abstract
A miniature dachshund aged 9 years and 7 months with a history of polyuria/polydipsia and depression was referred. General physical and neurological examinations revealed no obvious abnormalities. MRI of the brain revealed a large space-occupying lesion in the left frontal lobe. This was surgically removed and pathologically diagnosed as a primitive neuroectodermal tumor (PNET). Although the clinical signs had been improved, follow-up MRI revealed recurrence of the tumor. Lomustine was administered, but 1 year after surgery, the dog exhibited cluster seizures and died. This is the first reported case of a dog with PNET confined to the forebrain region treated by surgical resection in combination with chemotherapy, as observed by repeated follow-up MRI.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27430318/