Peer-reviewed veterinary case report
Case of bilateral seminoma in a trotter stallion.
- Journal:
- Reproduction in domestic animals = Zuchthygiene
- Year:
- 2010
- Authors:
- Govaere, J et al.
- Affiliation:
- Department of Reproduction
- Species:
- horse
Plain-English summary
This report discusses a case of a stallion, which is a male horse, that had a type of testicular tumor called a bilateral seminoma. After the horse was slaughtered, a detailed examination of the tumor showed that it was made up mostly of specific tumor cells with large nuclei and very little surrounding cytoplasm. The growth rate of these cells was low, as indicated by a special test called Ki67 staining, which showed only 4% of the cells were actively dividing. This study is notable because it is the first to use this particular staining method to assess the growth rate of testicular seminomas in stallions.
Abstract
This report describes a bilateral seminoma in a stallion. After slaughter, histological examination revealed that the tumour consisted predominantly of polyhedral tumour cells with large nuclei, obvious nucleoli and a small border of cytoplasm. The mitotic index was low and Ki67 staining revealed 4% nuclear staining. To our knowledge, this paper is the first using Ki67 staining as a method to evaluate the mitotic rate in a testicular seminoma in the stallion.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/18954387/