Peer-reviewed veterinary case report
Dog with spinal injury treated with amniotic stem cells
By Eun Young Kim et al.·Published in Veterinary and Animal Science·2023·MKbiotech Co., Ltd. , 99 Daehak-ro, Yuseong-gu, Daejeon 34134, Republic of Korea, NL·View original on DOAJ →
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Original publication title: Case report: Amniotic fluid-derived mesenchymal stem cell treatment in a dog with a spinal cord injury
- Species:
- dog
Plain-English summary
A 2-year-old male beagle was brought in after suffering a spinal cord injury that left him unable to control his legs and other bodily functions. The vet performed surgery to relieve pressure on the spine and injected stem cells derived from amniotic fluid directly into the damaged area. About 15 to 16 weeks later, the dog showed significant improvement in his hind limb movement and was able to walk on his own, although not perfectly. This case suggests that stem cell therapy could be a helpful treatment for dogs with spinal cord injuries.
People also search for: dog spinal cord injury treatment · beagle unable to walk · stem cell therapy for dogs
Abstract
Spinal Cord Injury (SCI) refers to complete or incomplete damage to the spinal cord, which comprises the central nervous system. SCI in dogs, like humans, is mostly caused by external trauma, and the degree of impact is dependent on the location of the injury in the spine. Stem cell therapy is a promising avenue for SCI research. In this report, we investigate the therapeutic potential of amniotic fluid-derived mesenchymal stem cells (AF-MSCs) in dogs with spinal cord injuries. A 2-year-old male beagle dog presented with sensory and motor incomplete symptoms resulting in an inability to control the legs, hips, and genitourinary system due to an injury in the lumbar region of the spinal cord. In addition to the administration of surgical decompression, AF-MSCs were directly injected into the damaged spinal tissue. Approximately 15–16 weeks after stem cell transplantation, the dog's hind limb movement improved, and spinal cord regeneration was confirmed through magnetic resonance imaging (MRI). Eventually, the dog was able to walk independently, although not perfectly. In conclusion, AF-MSC-based stem cell transplantation may be beneficial for SCIs.
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Search related cases →Original publication on DOAJ: https://doi.org/10.1016/j.vas.2023.100318