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Peer-reviewed veterinary case report

Case report: An outbreak of herpesvirus myeloencephalitis in vaccinated horses.

Journal:
The Canadian veterinary journal = La revue veterinaire canadienne
Year:
1979
Authors:
Thomson, G W et al.
Species:
horse

Plain-English summary

In 1977, during the foaling season, five vaccinated Standardbred horses at a breeding stable developed a serious brain and spinal cord infection caused by the equine herpesvirus. Other horses on the property also showed signs of respiratory illness and some experienced abortions. Tests revealed that the virus was found in the brain of one horse with the brain infection and in the lungs of two aborted foals. Additionally, most of the horses tested showed a significant increase in antibodies against the virus, indicating they had been exposed. The outbreak highlighted that even vaccinated horses can be affected by this virus.

Abstract

In the foaling season of 1977, five vaccinated horses in a Standardbred breeding stable were affected with herpesvirus myeloencephalitis. Respiratory and abortigenic forms also occurred in other individuals on the premises. Equine herpesvirus type 1 was isolated from the brain of one case of myeloencephalitis and from lungs of two aborted fetuses. Twelve of 16 horses demonstrated fourfold or greater increases in titres to equine herpesvirus type 1.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/216473/