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Peer-reviewed veterinary case report

Dog with neck pain and seizures diagnosed with spinal vein blood clot

By Rute Canejo-Teixeira et al.·Published in Frontiers in Veterinary Science·2026·Division of Clinical Radiology, Department of Clinical Veterinary Science, Vetsuisse Faculty, University of Bern, Bern, Switzerland, CH·View original on DOAJ

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Original publication title: Case Report: Cervical internal vertebral venous plexus thrombosis diagnosed using time-of-flight magnetic resonance angiography in a dog

Species:
dog

Plain-English summary

A 13-year-old male Siberian Husky was brought in with severe neck pain, limping in his left front leg, and having seizures. Tests showed he had a urinary tract infection and some abnormal blood results. An MRI of his neck revealed a blockage in a vein in his spine, which was confirmed using a special imaging technique called time-of-flight magnetic resonance angiography (TOF-MRA). This non-invasive method helped diagnose a blood clot in the vein, and understanding this condition can help vets treat similar cases in the future.

People also search for: dog neck pain · Siberian Husky seizures · dog blood clot treatment

Abstract

BackgroundTime-of-Flight (TOF) magnetic resonance angiography (MRA) is a non-contrast imaging technique used for vascular assessment but underexplored in veterinary spinal imaging. This case report presents the use of TOF-MRA at 3 Tesla to diagnose cervical internal vertebral venous plexus (IVVP) thrombosis in a dog, advancing the application of three-dimensional imaging in veterinary neurology.Case presentationA 13-year-old castrated male Siberian Husky presented with acute cervical pain, left thoracic limb lameness, and generalized tonic–clonic epileptic seizures. Laboratory findings revealed mild neutrophilia (10.83 × 10^9/L), elevated fibrinogen (404 mg/dL), and a urinary tract infection (bacteriuria, leukocyturia, and proteinuria).Diagnosis and outcomePre- and post-contrast MRI examination of the head revealed no abnormalities of the brain. A delayed post-contrast conventional T2-weighted MRI sequence of the cervical spine demonstrated focal loss of normal flow void of the left IVVP at the C4-C5 level. Three-dimensional TOF-MRA showed a corresponding focal signal void in the left ventral IVVP from C4 to C5 and an associated venous dilation consistent with thrombosis.ConclusionThis case demonstrates TOF-MRA’s potential as a non-invasive, contrast-free method for diagnosing spinal venous thrombosis in dogs. It underscores the importance of vascular imaging in dogs with acute neurological signs, offering valuable insights for veterinary practice and future research.

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Original publication on DOAJ: https://doi.org/10.3389/fvets.2026.1778813