Peer-reviewed veterinary case report
Dog with back leg weakness caused by spine bone overgrowth
By Max Foreman et al.·Published in Frontiers in Veterinary Science·2022·Neurology and Neurosurgery Service, Dick White Referrals, Part of Linnaeus Veterinary Limited, Cambridgeshire, United Kingdom, CH·View original on DOAJ →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Case Report: Diffuse Lumbar Hyperostosis Causing Vertebral Canal Stenosis in a Dog With Concurrent Multicentric T-Cell Lymphoma
- Species:
- dog
Plain-English summary
A 4-year-old female Bullmastiff-cross was brought in because she had been having trouble walking for the past day. A neurological exam showed issues with her spinal cord, and an MRI revealed that her vertebrae were abnormally thickened, causing narrowing of the spinal canal. Tests also showed she had T-cell lymphoma, a type of cancer. Unfortunately, due to the severity of her condition and poor prognosis, the decision was made to euthanize her. This case highlights a rare condition where cancer can lead to bone changes in the spine.
People also search for: dog trouble walking · Bullmastiff lymphoma treatment · paraparesis in dogs · dog spinal canal narrowing · dog cancer prognosis
Abstract
A 4-year-old female spayed Bullmastiff-cross presented with a 24-h history of progressive paraparesis. Neurological examination was consistent with L4–S3 myelopathy. On magnetic resonance imaging (MRI), all vertebrae showed homogenously increased short tau inversion recovery (STIR) signal with strong contrast enhancement. The vertebral canal was concentrically narrowed along the length of the L5 vertebra secondary to bony proliferation of the vertebral pedicles, dorsal lamina, and vertebral body. Cytological analysis of the peripheral lymph nodes and subsequent flow cytometry was consistent with T-cell lymphoma. The dog was euthanised due to poor prognosis. Necropsy confirmed the presence of stage V multicentric T-cell lymphoma, as well as diffuse hyperostosis of the vertebral bodies. This is the first report of presumed paraneoplastic lumbar skeletal hyperostosis.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on DOAJ: https://doi.org/10.3389/fvets.2022.825525