Peer-reviewed veterinary case report
Vomiting Maltese dog developed stomach polyps from long-term
By Lee, Haemin et al.·Published in Frontiers in veterinary science·2023·College of Veterinary Medicine, South Korea·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Case report: Fundic gland polyps caused by long-term omeprazole use in a Maltese dog.
- Species:
- dog
Plain-English summary
A 5-year-old Maltese dog was brought in for chronic vomiting after being treated with omeprazole, a medication used to reduce stomach acid, for over four years. An ultrasound showed thickening of the stomach wall, and an endoscopy revealed polyps in the stomach lining. After stopping the omeprazole, the dog's condition improved, and follow-up ultrasounds showed that the polyps had resolved. This case highlights the potential side effects of long-term omeprazole use in dogs.
People also search for: Maltese dog vomiting treatment · omeprazole side effects in dogs · dog stomach polyps treatment
Abstract
Long-term use of proton-pump inhibitors can induce fundic gland polyps in the human stomach. However, this phenomenon has not been described in the veterinary literature. A 5-year-old intact female Maltese dog was referred to our hospital with chronic intermittent vomiting. The dog had been administered omeprazole (0.7-1.0 mg/kg PO q24 h) for the management of hydrocephalus for over 4 years; the omeprazole dose was increased to 10 mg/kg PO q24 h 8 months prior to presentation at referring hospital. Abdominal ultrasonography revealed marked thickening of the gastric wall with multi-lobulated, thickened folds. Subsequent endoscopy revealed marked polypoid lesions, and histological examination of the biopsy samples was consistent with the fundic gland polyps associated with proton-pump inhibitor use in humans. The lesions resolved after cessation of omeprazole, as assessed by ultrasonography. This report describes a case of fundic gland polyps following the long-term administration of omeprazole in a dog.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37937150/