Peer-reviewed veterinary case report
Mineralized blood clots in lung arteries of two dogs
By Suzanne Rosen et al.·Published in Frontiers in Veterinary Science·2020·View original on DOAJ →
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Original publication title: Case Report: Mineralized Pulmonary Artery Thrombi in Two Dogs Treated for Meningoencephalitis of Unknown Origin
- Species:
- dog
Plain-English summary
Two dogs diagnosed with a serious brain condition called meningoencephalitis of unknown origin (MUO) were treated with long-term corticosteroids and another medication. Although this condition usually has a poor outlook, both dogs lived longer than expected before developing breathing problems due to mineralized clots in their lung arteries. Unfortunately, they eventually passed away due to these respiratory issues. The study discusses potential side effects of the medications that may have contributed to these complications.
People also search for: dog meningoencephalitis treatment · dog breathing problems after medication · long-term effects of corticosteroids in dogs
Abstract
Meningoencephalitis of unknown origin (MUO) is a relatively common and very serious canine neurologic condition, which is typically associated with a poor long term prognosis despite treatment. This case series chronicles two dogs diagnosed with MUO who were treated with long term corticosteroids and cytosine arabinoside and lived well-beyond the typical survival time for this condition. Both eventually succumbed to respiratory signs associated with mineralized thrombi in their pulmonary arteries. Adverse effects from the two drugs used for treatment are reviewed in order to propose a possible mechanism to explain how long term use of these medications could result in such a phenomenon.
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Search related cases →Original publication on DOAJ: https://doi.org/10.3389/fvets.2020.569597