Case Report: Molecular and Pathological Investigations of ZoonoticSpp.-Induced Ulcerative Pododermatitis in a Domestic Cat in Thailand.

Abstract

spp. is a group of trichuroid nematodes that mainly infect non-human primates and domestic cats. The lifecycle of these nematodes remains unclear. In non-human primates,spp. were found in the nasal cavity. However, ulcerative dermatitis has been reported in infected cats. An adult, intact, female domestic short-haired cat was presented with ulcerative pododermatitis of all limbs. Punch biopsy was performed at the edge of the ulcerative wound for histopathological investigation and showed necrosis and infiltration of inflammatory cells around the nematode-like lesion. Eggs with-like characteristics were present. Tissue sections were subjected to DNA extraction and PCR targeting, using primers designed from. The phylogenetic tree revealed that DNA obtained from the lesion of the domestic cat was grouped withspp. from the olive glass mouse ()and, both from the red fox (). The study is the first report of feline anatrichosomiasis in Thailand, and we present both pathological findings and molecular evidence. The cat was successfully treated with emodepsine/praziquantel. The skin lesion recovered within 3 days after anthelmintic treatment. Becausespp. have been reported in humans, the zoonotic potential of this parasite should be considered.