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Peer-reviewed veterinary case report

Bone regrowth after partial jaw removal in a 3-month-old French

By Wright, Alexandra L et al.·Published in Frontiers in veterinary science·2023·Department of Clinical Sciences, United States·View original on PubMed

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Original publication title: Case report: Spontaneous mandibular body regeneration following unilateral subtotal mandibulectomy in a 3-month-old French bulldog.

Species:
dog

Plain-English summary

A 3-month-old male French bulldog was brought in with a tumor in his jaw, which was diagnosed as oral squamous cell carcinoma. The vet performed surgery to remove part of his jaw, and after eight weeks, during a follow-up visit, they discovered that the bone in the jaw had completely regenerated. This remarkable recovery meant that the puppy did not need any further treatment for jaw alignment issues. The case shows that young dogs can heal remarkably well after such surgeries.

People also search for: French bulldog jaw tumor treatment · dog jaw surgery recovery · spontaneous bone regeneration in dogs

Abstract

OBJECTIVE: To document a case of spontaneous regeneration of the mandibular body following subtotal mandibulectomy in a juvenile dog. CASE SUMMARY: A 3-month-old male intact French bulldog was presented with papillary oral squamous cell carcinoma located at the dorsal aspect of the molar region of the left mandible. Initial biopsy of the mass was performed by the primary care veterinarian. Complete clinical staging revealed no signs of metastasis. Computed tomographic images of the head showed minimal contrast enhancement of the mass with no signs of periosteal or bone involvement. Subtotal mandibulectomy was performed. Histopathology indicated complete excision of the tumor. The patient returned 8-weeks later for follow up and cleft palate surgical repair, at which time bone was noted in the mandibulectomy area on palpation. Repeat computed tomography of the head revealed complete regeneration of the left mandibular body from the level of the ramus to the mandibular symphysis. No treatment for malocclusion was necessary due to the reformation of a functional mandible. CLINICAL RELEVANCE: The present case demonstrates that spontaneous regeneration of the mandibular body is possible following subtotal mandibulectomy in immature dogs. Subtotal mandibulectomy is a radical procedure that can lead to long term complications including mandibular drift, malocclusion, and oral pain. This case report provides evidence that these sequelae may be mitigated or eliminated in young patients undergoing this procedure.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37901099/