Peer-reviewed veterinary case report
Dog treated successfully with IV lipid therapy after amphetamine
By Harris, Stephanie et al.Ā·Published in Frontiers in veterinary scienceĀ·2022Ā·Department of Clinical Sciences, United StatesĀ·View original on PubMed ā
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research ā every detail traces back to the citation above. How we work ā
Original publication title: Case Report: Successful Intravenous Lipid Emulsion Therapy for Canine Amphetamine Toxicosis.
- Species:
- dog
Plain-English summary
A 4-year-old mixed breed dog was brought to the vet after accidentally ingesting a large amount of Adderall, a medication containing amphetamines. She showed signs of agitation, rapid heart rate, and high blood pressure. The vet treated her with intravenous lipid emulsion therapy, which helped lower the levels of amphetamine in her blood. Remarkably, she improved significantly and was able to go home less than 24 hours after treatment. This case highlights a new treatment option for dogs suffering from amphetamine poisoning.
People also search for: dog amphetamine poisoning treatment Ā· what to do if my dog ate Adderall Ā· signs of dog drug overdose
Abstract
A 4-year-old, female-spayed, mixed breed dog, weighing 24.2 kg, was presented for acute ingestion of ~12.3 mg/kg of Adderall XR, an extended-release amphetamine medication. In dogs, the oral median lethal dose for amphetamines ranges anywhere from 9-11 mg/kg to 20-27 mg/kg. On presentation, the patient was agitated, tachycardic and hypertensive. Initial treatment was instituted with intravenous lipid emulsion (IVLE) therapy, and baseline and post-treatment amphetamine concentrations were quantified in serum and plasma. In both serum and plasma, post-IVLE concentrations of amphetamine were lower 1 h after treatment and IVLE was the only treatment instituted during this time. The dog improved significantly while in hospital and was discharged <24 h after presentation. This is the first known reported use of IVLE for treatment of amphetamine toxicosis with documented decreases in both serum and plasma amphetamine levels shortly after administration of IVLE.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases āOriginal publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35903141/