Peer-reviewed veterinary case report
Dog treated successfully with IV lipid therapy for amphetamine
By Stephanie Harris et al.·Published in Frontiers in Veterinary Science·2022·Department of Clinical Sciences, Auburn University College of Veterinary Medicine, Auburn, AL, United States, CH·View original on DOAJ →
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Original publication title: Case Report: Successful Intravenous Lipid Emulsion Therapy for Canine Amphetamine Toxicosis
- Species:
- dog
Plain-English summary
A 4-year-old female mixed breed dog was brought to the vet after accidentally eating a large amount of Adderall, a medication containing amphetamines. She showed signs of agitation, a fast heart rate, and high blood pressure. The vet treated her with intravenous lipid emulsion therapy, which helped lower the levels of amphetamine in her blood. Remarkably, the dog improved quickly and was able to go home less than 24 hours after her treatment.
People also search for: dog ate Adderall treatment · amphetamine poisoning in dogs · intravenous lipid therapy for dogs
Abstract
A 4-year-old, female-spayed, mixed breed dog, weighing 24.2 kg, was presented for acute ingestion of ~12.3 mg/kg of Adderall XRⓇ, an extended-release amphetamine medication. In dogs, the oral median lethal dose for amphetamines ranges anywhere from 9–11 mg/kg to 20–27 mg/kg. On presentation, the patient was agitated, tachycardic and hypertensive. Initial treatment was instituted with intravenous lipid emulsion (IVLE) therapy, and baseline and post-treatment amphetamine concentrations were quantified in serum and plasma. In both serum and plasma, post-IVLE concentrations of amphetamine were lower 1 h after treatment and IVLE was the only treatment instituted during this time. The dog improved significantly while in hospital and was discharged <24 h after presentation. This is the first known reported use of IVLE for treatment of amphetamine toxicosis with documented decreases in both serum and plasma amphetamine levels shortly after administration of IVLE.
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Search related cases →Original publication on DOAJ: https://doi.org/10.3389/fvets.2022.938021