Peer-reviewed veterinary case report
Dog with intestinal muscle inflammation treated successfully with IV
By Olivarez, Michelle Patrick et al.·Published in Frontiers in veterinary science·2024·Southeast Veterinary Referral Center, United States·View original on PubMed →
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Original publication title: Case report: Successful treatment of intestinal leiomyositis in a dog using adjunctive intravenous immunoglobulin.
- Species:
- dog
Plain-English summary
A 10-year-old spayed female Dachshund was brought in with severe abdominal pain and trouble moving her bowels. After surgery, the vet found that she had a serious condition called intestinal leiomyositis, which is inflammation of the intestines. To treat her, the vet gave her a special treatment called intravenous immunoglobulin (hIVIG) along with other medications. Within 10 days, her bowel function improved, and her symptoms went away. With continued treatment, she maintained her recovery and was able to live comfortably.
People also search for: Dachshund abdominal pain treatment · dog intestinal inflammation · hIVIG for dogs · dog ileus recovery · dog bowel problems treatment
Abstract
A 10-year-old spayed female Dachshund presented with abdominal pain and generalized severe ileus. An exploratory laparotomy was performed, confirming a severe ileus of undetermined origin. Multiple intestinal biopsy results confirmed acute intestinal leiomyositis. Immunohistochemistry (IHC) stains confirmed a T-cell predominant inflammatory infiltrate. Intravenous immunoglobulin (hIVIG) was administered prior to immunosuppressive therapy. Within 10 days of hIVIG treatment, functional peristaltic activity returned, and symptoms resolved. Long-term management, including the use of mycophenolate, resulted in sustained functional peristaltic recovery. Further studies are needed to explore the potential benefits of hIVIG treatment in the stabilization phase of this commonly fatal, treatment-refractory disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39109347/