Peer-reviewed veterinary case report
Surgical removal of urethral cancer in two female dogs
By Chung, Wookhun et al.·Published in Frontiers in veterinary science·2026·Nowon N Animal Medical Center, South Korea·View original on PubMed →
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Original publication title: Case Report: Surgical excision of urethral transitional cell carcinoma by total urethrectomy combined with partial cystectomy and vesicovaginal urinary diversion in two female dogs.
- Species:
- dog
Plain-English summary
Two female dogs with a type of bladder cancer called transitional cell carcinoma (TCC) were treated with surgery to remove their entire urethra and part of their bladder. This procedure also involved creating a new pathway for urine to flow from the bladder to the vagina. Both dogs recovered well after surgery, and while chemotherapy was suggested, it was only given to one of the dogs. Remarkably, there were no signs of cancer returning for about one to one and a half years after the surgery. This surgical approach appears to be a successful option for treating localized TCC in female dogs.
People also search for: dog bladder cancer treatment · transitional cell carcinoma in dogs · female dog urinary obstruction surgery
Abstract
Transitional cell carcinoma (TCC), or urothelial carcinoma, is the most common malignant tumor of the canine urinary bladder or urethra, often causing urinary obstruction. While chemotherapy is generally considered as primary management, surgical treatments, including total or partial cystectomy, have occasionally been reported. This report describes two cases of canine urethral TCC managed with total urethrectomy combined with partial cystectomy and vesicovaginal urinary diversion. In both cases, the entire urethral segment and distal urinary bladder were removed while preserving the ureteral orifices. Ventral cystostomy was performed to expose the masses, and special care was taken to maintain vascular supply to the bladder. Postoperative recovery was uneventful. Although chemotherapy was recommended, it was performed in only one case. Urinary flow from the urinary bladder to vagina was successfully diverted without ureteral reimplantation. No recurrence was observed for approximately one year postoperatively in Case 1 and one and a half years in Case 2, respectively. These findings suggest that total urethrectomy combined with partial cystectomy and vesicovaginal urinary diversion is a feasible and effective surgical approach for localized urethral TCC in female dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/42158320/