Peer-reviewed veterinary case report
Cat with esophageal strictures developed fatal systemic
By Hammond, Tara et al.·Published in Frontiers in veterinary science·2026·Department of Emergency and Critical Care, United States·View original on PubMed →
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Original publication title: Case Report: Systemic reactive angioendotheliomatosis in a young cat with a history of esophageal strictures and balloon dilations.
- Species:
- cat
Plain-English summary
A 3.3-year-old male domestic shorthair cat was brought to the emergency vet with neurological issues, including seizures. He had a history of esophageal strictures that had been treated with balloon dilations. Unfortunately, tests showed severe blood problems, and his condition worsened quickly, leading to cardiac arrest. A necropsy revealed he had a rare and fatal disease called feline systemic reactive angioendotheliomatosis (FSRA), which is linked to previous tissue trauma and inflammation. Sadly, there are no effective treatments for this condition, and it is considered uniformly fatal.
People also search for: cat seizures · cat neurological problems · feline systemic reactive angioendotheliomatosis · cat cardiac arrest · cat esophageal stricture treatment
Abstract
A 3.3-year-old castrated male domestic shorthair cat presented to the emergency service with neurologic signs. The cat had an extensive medical history, including previous treatment for esophageal strictures via balloon dilation. Diagnostics revealed a coagulopathy, a highly regenerative anemia, and marked thrombocytopenia. The cat's neurologic signs progressed rapidly, culminating in seizures and cardiac arrest. A necropsy revealed findings consistent with feline systemic reactive angioendotheliomatosis (FSRA), a rare, idiopathic, multisystemic, and uniformly fatal disease. To date, only 16 cases of FSRA have been reported in the veterinary literature, and very few provide detailed descriptions of attempted treatments. It is theorized that repeated tissue trauma from procedures, infection, and chronic inflammation may have triggered a more systemic response, contributing to the development of FSRA in this cat. Further investigation is needed to better understand this rare disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/42058556/