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Peer-reviewed veterinary case report

Dog with liver iron overload seen on ultrasound and CT scans

By Mihyun Choi & Namsoon Lee·Published in Frontiers in Veterinary Science·2024·BON Animal Medical Center, Suwon, Republic of Korea, CH·View original on DOAJ

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Original publication title: Case report: Ultrasonographic and computed tomographic imaging features of hemochromatosis in a dog

Species:
dog

Plain-English summary

A 5-year-old mixed-breed dog was brought to the vet because he was not eating and had high liver enzyme levels. Imaging tests showed that his liver was enlarged and had unusual features, along with swollen lymph nodes. A biopsy confirmed that he had a condition called hemochromatosis, which means there was too much iron stored in his liver. This case is notable because it's the first time this condition has been diagnosed using imaging in a dog.

People also search for: dog liver disease symptoms · why is my dog not eating · hemochromatosis in dogs treatment

Abstract

A castrated male mixed-breed dog weighing 7 kg presented with elevated liver enzymes and anorexia. Abdominal radiography revealed hepatomegaly with heterogeneous hepatic opacification, and abdominal ultrasonography showed a fine echotexture and heterogeneous parenchyma concurrent with a suspected acquired portosystemic shunt. Pre-contrast computed tomography (CT) showed marked hepatomegaly with homogeneous increased liver density and multiple enlarged abdominal lymph nodes with markedly increased parenchymal density. Histopathology of the hepatic and lymph node biopsy revealed accumulated abundant hemosiderin, and the Prussian Blue stain confirmed marked iron accumulation within the hepatocytes. Based on our review of the literature, this is the first case report describing the imaging diagnosis of hemochromatosis in a dog.

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Original publication on DOAJ: https://doi.org/10.3389/fvets.2023.1331392