Peer-reviewed veterinary case report
Using Omnigen amnion to treat corneal ulcers in cats and dogs
By Maini, Serena et al.·Published in Topics in companion animal medicine·2020·Department of Clinical Science and Services, United Kingdom·View original on PubMed →
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Original publication title: Case Series Describing the Use of Low-Temperature Vacuum-Dehydrated Amnion (Omnigen) for the Treatment of Corneal Ulcers in Cats and Dogs: 46 Cases (2016-2017).
Plain-English summary
A group of cats and dogs with corneal ulcers (painful eye sores) were treated using a new product called Omnigen, which is a type of amniotic membrane. Out of 46 eyes treated, 43 healed successfully, and most of the pets regained their vision. Omnigen was used in different ways: as a standalone treatment, as a supplement to other treatments, or as a patch. While there were some cases where the graft didn't work, the overall results were very positive, showing that Omnigen can be an effective option for treating these eye problems in pets.
People also search for: dog corneal ulcer treatment · cat eye problems · Omnigen for pets · corneal graft success rate · brachycephalic dog eye issues
Abstract
Amniotic membrane is widely used in the treatment of ocular surface disorders in human and veterinary patients. Preservation and storage of amnion has proven challenging, prompting the development of new preservation techniques. Omnigen, a novel low-temperature vacuum-dehydrated amnion, is reported to possess enhanced structural properties and biochemical stability in vitro, but its clinical use in veterinary patients is not well described. This study aims to document and describe the varied use of Omnigen for the surgical treatment of corneal ulceration in cats and dogs. A total of 45 patients (46 eyes) were recruited from the clinical record system of the Royal Veterinary College (London) between January 2016 and December 2017. Brachycephalic breeds were over-represented (37/45; 82.2%). Omnigen was used as a standalone graft in 5/46 (10.9%) eyes, as a supplementary graft in 29/46 (63.0%) eyes and as a patch in 12/46 (26.1%) eyes. Graft failure occurred in 10/46 eyes (21.7%). At final examination 43/46 eyes (93.5%) had healed and 31/33 eyes (93.9%) were visual. This study demonstrates the successful use of Omnigen for the surgical treatment of corneal ulceration in cats and dogs. Further studies are needed to clarify its properties and benefits in the clinical field.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32919060/