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Peer-reviewed veterinary case report

Cats with early chronic rhinosinusitis have worse nasal and sinus

By Beauvois, Marine et al.·Published in Journal of the American Veterinary Medical Association·2023·View original on PubMed

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Original publication title: Cats with idiopathic chronic rhinosinusitis that develop clinical signs before two years of age have more severe nasal conchal lysis, sinus malformation, and more severe inflammation on histological examination.

Species:
cat

Plain-English summary

A group of young cats under two years old with chronic nasal issues (feline idiopathic chronic rhinosinusitis) showed more severe damage to their nasal structures compared to older cats with the same condition. The younger cats had more significant inflammation and malformations in their sinuses, which could lead to worse symptoms. This suggests that if a cat develops these nasal problems at a young age, they may experience more severe health issues. Treatment options may need to be adjusted based on the severity of the condition observed in younger cats.

People also search for: cat nasal problems · chronic rhinosinusitis in young cats · cat sinus infection treatment

Abstract

OBJECTIVE: To evaluate the severity of sinonasal lesions on CT in cats with feline idiopathic chronic rhinosinusitis (FICR) comparing cats who developed the condition at a young age to those who developed it as an adult. And, to assess if CT findings correlate with histopathology. ANIMALS: 58 cats with FICR confirmed on histopathology. METHODS: Medical records were retrospectively reviewed. Cats were divided into 2 groups based on their age category: juvenile (group 1, n = 30) and adult (group 2, 28), with juvenile cats being 2 years old or younger and adults being older than 2 years at the onset of clinical signs. Computed tomographic findings were recorded and graded (mild, moderate, and severe) by a board-certified radiologist, comparing each group. The CT findings were then compared to the histopathology results. RESULTS: The overall CT grade was not significantly different between the 2 groups (P = .21). Nasal conchal lysis was more severe in group 1 than in group 2 (P = .002), and group 1 also had a higher incidence of sinusal malformation (OR 2.42). Inflammatory infiltrates were more severe on histopathology in group 1 than in group 2 (OR 4.95), and the overall CT grade was slightly positively associated with the histological severity (κ = 0.2). CLINICAL RELEVANCE: Feline idiopathic chronic rhinosinusitis was associated with more severe nasal conchal lysis, sinus malformation, and more severe inflammation on histopathological examination in cats that develop clinical signs before 2 years of age. This finding could have an impact in term of clinical signs severity.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37380164/