Peer-reviewed veterinary case report
Cell biological and molecular characteristics of pseudorabies virus infections in cell cultures and in pigs with emphasis on the respiratory tract.
- Journal:
- Veterinary research
- Year:
- 2007
- Authors:
- Nauwynck, Hans et al.
- Affiliation:
- Faculty of Veterinary Medicine
Abstract
In the present review, several cell biological and molecular aspects of virus-cell and virus-host (pig) interactions are reviewed for pseudorabies (Aujeszky's disease) virus. Concerning the virus-cell interactions, the complex cascade of events in the virus replication cycle is given together with the different mechanisms of cell-to-cell spread. The pathogenesis of pseudorabies virus infections in pigs is concentrated on the sequence of events in the respiratory tract. Finally, a short overview is given on the control of the disease and eradication of the virus by the combination of marker vaccines and discriminating ELISA.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/17257571/