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Peer-reviewed veterinary case report

Cell tropism and entry of porcine circovirus 2.

Journal:
Virus research
Year:
2012
Authors:
Nauwynck, H J et al.
Affiliation:
Faculty of Veterinary Medicine

Abstract

Porcine circovirus 2 (PCV2) may induce reproductive failure (return to oestrus, embryonic death, mummification, weak- and stillborn piglets) and postweaning multisystemic wasting syndrome (PMWS). Furthermore, it may modulate the immunity in such a way that it aggravates the outcome of many bacterial and viral infections. In the present paper, the cellular tropism and entry of PCV2 are described and linked with the pathological and clinical consequences.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/22100402/