Peer-reviewed veterinary case report
Central diabetes insipidus in young cats treated with oral
By Aroch, Itamar et al.·Published in Journal of Feline Medicine and Surgery·2005·School of Veterinary Medicine, The Hebrew University of Jerusalem, PO Box 12, Rehovot 76–100, Israel·View original on Crossref →
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Original publication title: Central diabetes insipidus in five cats: Clinical presentation, diagnosis and oral desmopressin therapy
- Species:
- cat
Plain-English summary
Five young domestic shorthair cats, all under 3 years old, were brought in with symptoms of excessive thirst and urination. They showed signs of dehydration and had trouble concentrating their urine. After tests confirmed they had central diabetes insipidus, the cats were treated with oral desmopressin, which helped them concentrate their urine better. All the cats responded well to the treatment, making it a good option for pet owners who prefer not to use nasal or eye drops.
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Abstract
Five cases of central diabetes insipidus (CDI) in domestic shorthair cats are described. All cats were under 3 years of age at the onset of clinical signs, and outdoor or outdoor/indoor cats, in which a prior trauma was either present or possible. The history included polydipsia and polyuria, and physical examination abnormalities included urinary bladder distention and dehydration. All cats had hyposthenuria with a urine specific gravity between 1.003 and 1.006. The diagnosis was confirmed by an observed inability to concentrate urine during a water deprivation test or compatible serum osmolality, followed by an increase in urine concentration after desmopressin administration. All cats in this report were treated successfully with oral desmopressin. The dose (25–50 μg q8–12h) and the response to therapy were variable. Oral desmopressin administration may serve as an effective alternative route for cat owners who find the conjunctival or nasal application of the solution an inconvenient mode of therapy.
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Search related cases →Original publication on Crossref: https://doi.org/10.1016/j.jfms.2005.03.008