Peer-reviewed veterinary case report
Brain tumor with ependymal cells in 18-month-old Australian terrier
By Headley, S A et al.·Published in Journal of comparative pathology·2009·Department of Basic Veterinary Sciences·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Central primitive neuroectodermal tumour with ependymal differentiation in a dog.
- Species:
- dog
Plain-English summary
An 18-month-old female Australian terrier was brought in after showing signs of central nervous system disease and sadly passed away. A large tumor in her brain replaced parts of the thalamus and hypothalamus, causing serious health issues. The tumor was identified as a central primitive neuroectodermal tumor (PNET) with ependymal differentiation, which is a rare type of brain tumor in dogs. Unfortunately, despite the diagnosis, the outcome was not favorable, and the dog did not survive.
People also search for: dog brain tumor symptoms · Australian terrier central nervous system disease · dog PNET treatment options
Abstract
A central primitive neuroectodermal tumour (PNET) with ependymal differentiation was identified in an 18-month-old female Australian terrier dog that died following signs of central nervous system disease. A large space-occupying haemorrhagic mass replaced the thalamus and part of the hypothalamus of the brain. Microscopical examination revealed a tumour formed by a compact sheet of small cells that contained ependymal and perivascular pseudorosettes. Immunohistochemically, the neoplastic cells variably expressed glial fibrillary acidic protein, neuron-specific enolase, vimentin and cytokeratin, consistent with divergent differentiation of the tumour. This case is thought to represent the first description of PNET with ependymal differentiation in a dog.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19091324/