Peer-reviewed veterinary case report
Border collie dog collapsing after exercise
By Eminaga, S et al.·Published in The Journal of small animal practice·2012·Dick White Referrals, United Kingdom·View original on PubMed →
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Original publication title: Centronuclear myopathy in a Border collie dog.
- Species:
- dog
Plain-English summary
A 2-year-old male Border collie was brought to the vet after experiencing collapsing episodes in his back legs during exercise for the past year. The vet found that the dog had muscle wasting and signs of a neuromuscular disorder. Tests showed abnormal electrical activity in his muscles, and a biopsy confirmed he had centronuclear myopathy, a type of muscle disease. The dog started to improve with supportive treatments that included L-carnitine, co-enzyme Q10, and a vitamin B compound.
People also search for: Border collie muscle disease · dog collapsing after exercise · centronuclear myopathy treatment · dog muscle atrophy symptoms
Abstract
A two-year old, male entire Border collie was presented with a one-year history of exercise-induced collapsing on the pelvic limbs. Physical examination revealed generalised muscle atrophy. Neurological examination supported a generalised neuromuscular disorder. Electromyography revealed spontaneous electrical activity in almost all muscles. Unfixed and formaldehyde-fixed biopsy samples were collected from the triceps brachii, longissimus and vastus lateralis muscles. Histopathological, histochemical and ultrastructural examinations of biopsy specimens were consistent with either centronuclear or myotubular myopathy. The dog clinically improved with supportive treatment with L-carnitine, co-enzyme Q10 and vitamin B compound. To the authors' knowledge, this is the first report of centronuclear/myotubular myopathy in a Border collie.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23013377/