Peer-reviewed veterinary case report
Beagle puppy diagnosed with inherited cerebellar disease
By Kent, M et al.·Published in The Journal of small animal practice·2000·School of Veterinary Medicine, United States·View original on PubMed →
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Original publication title: Cerebellar cortical abiotrophy in a beagle.
- Species:
- dog
Plain-English summary
A beagle puppy was brought in showing signs of coordination problems, which are often linked to brain issues. Tests on the puppy's brain tissue revealed damage consistent with a condition called cerebellar abiotrophy, a genetic disorder that affects brain development. This condition is likely inherited and may be passed down from the puppy's parents. Unfortunately, there is no cure for this condition, and treatment options are limited to managing symptoms.
People also search for: beagle puppy coordination problems · cerebellar abiotrophy in dogs · inherited brain disorders in puppies
Abstract
A beagle puppy was presented with clinical signs indicative of a cerebellar disease. Histopathological evaluation of the cerebellum revealed a diffuse degenerative cortical lesion. The clinical history and the histopathological findings are consistent with a neonatal cerebellar abiotrophy. Furthermore, the breeding history supports the hypothesis of an inherited genetic disorder that is, most likely, an autosomal recessive trait.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10976629/