Peer-reviewed veterinary case report
Progressive balance loss in two Portuguese Podenco puppies
By van Tongern, S E et al.·Published in The veterinary quarterly·2000·Department of Veterinary Pathology, Netherlands·View original on PubMed →
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Original publication title: Cerebellar cortical abiotrophy in two Portuguese Podenco littermates.
Plain-English summary
Two Portuguese Podenco puppies developed problems with coordination and balance starting at just two to three weeks old. This condition, known as cerebellar cortical abiotrophy, leads to the loss of important brain cells that help control movement. Unfortunately, this is a progressive disease that affects their ability to walk and play normally. Since it is suspected to be inherited, it’s important for owners to be aware of this condition if they have puppies from the same litter.
People also search for: Portuguese Podenco puppy coordination problems · cerebellar ataxia in dogs · inherited dog diseases
Abstract
Cerebellar cortical abiotrophy in two Portuguese Podenco littermates is reported and discussed. The disease is characterized by progressive cerebellar ataxia with an early onset of two to three weeks. Extensive loss, degeneration, and necrosis of Purkinje cells particularly involved the cerebellar hemispheres. An autosomal recessive pattern of inheritance is suspected.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10952450/