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Peer-reviewed veterinary case report

Cocker Spaniel puppy with unsteady walk from cerebellar malformation

By Lim, Ji-Hey et al.·Published in Journal of veterinary science·2008·College of Veterinary Medicine, South Korea·View original on PubMed

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Original publication title: Cerebellar vermian hypoplasia in a Cocker Spaniel.

Species:
dog
Movement & jointsDogs

Plain-English summary

An eight-week-old female Cocker Spaniel was brought to the vet because she was having trouble coordinating her movements, showing signs like wobbliness and tremors. After several tests, including imaging of her skull, the vet found a cyst-like area in her brain that indicated a developmental issue. Unfortunately, the puppy's condition did not improve, and she was euthanized. A post-mortem examination confirmed that she had a brain malformation similar to a condition seen in humans called Dandy-Walker syndrome.

People also search for: Cocker Spaniel ataxia treatment · puppy tremors causes · brain malformation in dogs

Abstract

An eight-week-old female Cocker Spaniel was presented with ataxia, dysmetria and intention tremor. At 16 weeks, the clinical signs did not progress. Investigation including imaging studies of the skull and cerebrospinal fluid analysis were performed. The computed tomography revealed a cyst-like dilation at the level of the fourth ventricle associated with vermal defect in the cerebellum. After euthanasia, a cerebellar hypoplasia with vermal defect was identified on necropsy. A polymerase chain reaction amplification of cerebellar tissue revealed the absence of an in utero parvoviral infection. Therefore, the cerebellar hypoplasia in this puppy was consistent with diagnosis of primary cerebellar malformation comparable to Dandy-Walker syndrome in humans.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18487946/