Peer-reviewed veterinary case report
Brain blood vessel growth with clots in a Shih Tzu dog
By Sakurai, Masashi et al.·Published in The Journal of veterinary medical science·2011·Department of Veterinary Pathology, Japan·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Cerebral vascular hamartoma with thrombosis in a dog.
- Species:
- dog
Plain-English summary
A 7-year-old male Shih Tzu was diagnosed with a growth in the right side of his brain that was causing problems. This growth, called a cerebral vascular hamartoma, was made up of abnormal blood vessels and was associated with blood clots. The dog showed no specific symptoms mentioned, but such conditions can lead to neurological issues like seizures or changes in behavior. Treatment details weren't provided, but identifying the issue is the first step in managing any related symptoms.
People also search for: dog brain tumor symptoms · Shih Tzu seizures · dog neurological problems treatment
Abstract
A cerebral vascular hamartoma was identified in the frontal lobe, striatum and thalamus of the right side of the brain of a male, 7-year-old Shih Tzu. Histologically, the lesion consisted of thin-walled vessels, which showed various sizes and occasionally contained fibrin thrombi. These vascular walls were composed of a single layer of fibromuscular tissue lined by flat endothelium with various amount of collagen, but devoid of large coat of smooth muscles and elastic tissue. Immunohistochemically, the lining endothelial cells were positive for von Willebrand Factor antibody. Neuropil between the vessels was stained with Klüver-Barrera stain, and positive for synaptophysin and GFAP antibodies. Based on these findings, the lesion was diagnosed as vascular hamartoma, which might resemble venous malformation in humans.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21646748/