Peer-reviewed veterinary case report
Cocker Spaniel dog with progressive ataxia
By Minatel, L et al.·Published in Veterinary pathology·2000·Department of Pathology·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Ceroid-lipofuscinosis in a Cocker Spaniel dog.
- Species:
- dog
Plain-English summary
A 4-year-old female Cocker Spaniel was diagnosed with ceroid-lipofuscinosis, a neurodegenerative storage disease, after showing signs of progressive ataxia (loss of coordination) and proprioceptive deficits (difficulty sensing body position). Tests revealed abnormal pigment accumulation in her brain and spinal cord. While this condition has been seen in other Cocker Spaniels, this case did not show the typical brown discoloration of the intestines. Unfortunately, there is no cure for this disease, and treatment focuses on managing symptoms and providing supportive care.
People also search for: Cocker Spaniel ataxia treatment · dog neurodegenerative disease symptoms · ceroid-lipofuscinosis in dogs
Abstract
A neurodegenerative storage disease identified as ceroid-lipofuscinosis by light, fluorescence, and electron microscopic examinations was diagnosed in a 4-year-old female Cocker Spaniel dog with progressive ataxia and proprioceptive deficits. Stored pigment was found within neurons of the brain and spinal cord and in smooth muscle cells of the urinary bladder and small muscular arteries. The microscopic findings resembled those found in six other cases of generalized ceroid-lipofuscinosis in this breed. However, the brown discoloration of the intestines, which was the major gross lesion observed in those cases, was not found. This is the first report of the disease in Argentina.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11055878/