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Peer-reviewed veterinary case report

Challenging diagnosis--icterus associated with a single perforating duodenal ulcer after long-term nonsteroidal antiinflammatory drug administration in a dog.

Journal:
The Canadian veterinary journal = La revue veterinaire canadienne
Year:
2004
Authors:
Duerr, Felix M et al.
Affiliation:
University of Saskatchewan · Canada
Species:
dog

Abstract

A dog developed icterus, vomiting, and anorexia 2 wk after orthopedic surgery and treatment with meloxicam for approximately 1 y. Exploratory laparotomy revealed a single perforated duodenal ulcer. The most likely cause of the hyperbilirubinemia was intrahepatic cholestasis resulting from peritonitis associated with the perforation.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/15283521/