Peer-reviewed veterinary case report
How quickly blood sugar changes affect fructosamine in cats
By Link, Karl R & Rand, Jacquie S·Published in Journal of feline medicine and surgery·2008·School of Veterinary Science, Australia·View original on PubMed →
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Original publication title: Changes in blood glucose concentration are associated with relatively rapid changes in circulating fructosamine concentrations in cats.
- Species:
- cat
Plain-English summary
A group of healthy cats was studied to understand how quickly their blood sugar levels affected a specific protein called fructosamine. When the cats were given high levels of sugar, fructosamine levels rose significantly within 3-5 days and took about 20 days to stabilize. After stopping the sugar infusion, fructosamine levels returned to normal within 5 days. For cats with moderate high sugar levels, it took longer for fructosamine to rise and stabilize, but it returned to normal much faster. This information can help vets monitor blood sugar control in diabetic cats.
People also search for: cat high blood sugar symptoms · fructosamine levels in cats · how to manage diabetes in cats
Abstract
The aim of the study was to determine the time required for plasma fructosamine concentration to increase after the onset of hyperglycaemia and decrease after resolution of hyperglycaemia. Healthy cats (n=14) were infused to maintain either moderate hyperglycaemia (n=5) (actual mean glucose 17 mmol/l) or marked hyperglycaemia (n=9) (actual 29 mmol/l) for 42 days. Fructosamine exceeded the upper limit of the reference range (331 micromol/l) after 3-5 days of marked hyperglycaemia, took 20 days to plateau and, after cessation of infusion, took 5 days to return to baseline. Fructosamine concentration for moderate hyperglycaemia took longer to exceed the reference range (7 days, range 4-14 days), and fewer days to plateau (8 days) and return to baseline (1 day). In cats with moderate hyperglycaemia, fructosamine concentration mostly fluctuated under the upper limit of the reference range. The range of fructosamine concentrations associated with a given glucose concentration was wide. The critical difference for fructosamine was 33 micromol/l.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18990597/