Peer-reviewed veterinary case report
Blood zinc, copper, and oxidative stress changes in dogs
By Dimri, Umesh et al.·Published in Veterinary parasitology·2008·Indian Veterinary Research Institute, India·View original on PubMed →
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Original publication title: Changes in oxidative stress indices, zinc and copper concentrations in blood in canine demodicosis.
- Species:
- dog
Plain-English summary
A group of dogs with localized and generalized demodicosis (a skin condition caused by mites) showed signs of oxidative stress, which can harm their health. Blood tests revealed that these dogs had higher levels of certain harmful substances and lower levels of protective antioxidants compared to healthy dogs. Additionally, their blood zinc and copper levels were also lower. The findings suggest that adding antioxidant supplements could help manage this skin condition and improve the dogs' overall health.
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Abstract
Status of certain oxidative stress indices and zinc and copper concentrations in blood were estimated in dogs with localized demodicosis (LD) and generalized demodicosis (GD). In comparison to healthy control, erythrocytic lipid peroxides level and superoxide dismutase activity were significantly (P<0.01) higher in both LD as well as GD. However, level of reduced glutathione and activity of catalase were significantly (P<0.01) lower in both LD and GD. Blood zinc and copper levels in dogs with LD and GD were significantly (P<0.01) lower than healthy control. Significant (P<0.01) differences were also observed in different oxidative stress indices and zinc and copper levels in between LD and GD groups. From the present study, it was concluded that demodicosis is associated with oxidative stress and antioxidant supplementation may be beneficial in management of canine demodicosis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18440148/