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Peer-reviewed veterinary case report

Testosterone and sperm improved after 3 GnRH shots in 3 male Beagles

By Kawakami, Eiichi et al.·Published in The Journal of veterinary medical science·2005·Department of Reproduction, Japan·View original on PubMed

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Original publication title: Changes in plasma testosterone levels and semen quality after 3 injections of a GnRH analogue in 3 dogs with spermatogenic dysfunction.

Species:
dog

Plain-English summary

Three male Beagles with low testosterone levels and fertility issues were treated with three weekly injections of a hormone therapy called Buserelin. After the treatment, their testosterone levels increased significantly, peaking about 4 to 6 weeks later. Additionally, the number of sperm and their movement improved within 5 to 7 weeks after starting the injections. This suggests that this hormone treatment can temporarily enhance semen quality in dogs with certain fertility problems.

People also search for: dog fertility treatment · Beagle low testosterone · sperm quality in dogs · hormone therapy for male dogs

Abstract

Three male Beagles with low plasma luteinizing hormone and testosterone levels and spermatogenic dysfunction (SD-dogs) were given 3 weekly subcutaneous injections of a gonadotropin-releasing hormone analogue (Buserelin; GnRH-AB). The plasma T level of all of the SD-dogs increased and peaked at 4-6 weeks after the first injection. The total number of sperm and the sperm motility of the three SD-dogs increased 5-7 weeks after the first injection. Therefore, the authors concluded that 3 weekly injections of GnRH-AB transiently improves semen quality in some cases of canine spermatogenic dysfunction.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16397384/